Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors

@article{Weidner1995CurrentPM,
  title={Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors},
  author={Noel Weidner},
  journal={Breast Cancer Research and Treatment},
  year={1995},
  volume={36},
  pages={169-180}
}
Abundant evidence has shown that tumor growth and metastasis are dependent upon tumor angiogenesis (TA). TA refers to the growth of new vessels toward and within the tumor. Until TA occurs, tumors grow no larger than 2–4 mm in diameter. Also, TA is necessary at the beginning and at the end of the metastatic cascade of events. Thus, it seems reasonable that increasing intratumoral microvascular density (iMVD) might correlate with greater tumor aggressiveness, such as a higher frequency of… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
299 Citations
67 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 299 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 67 references

CD31: A new marker for vascular neoplasia

  • TA Longacre, RV Rouse
  • Adv Anat Pathol
  • 1994
1 Excerpt

CD34: A review

  • M van de Rijn, RV Rouse
  • Appl Immunohistochem
  • 1994
1 Excerpt

Influence of tumoral microvessel density on the recurrence-free survival in human breast cancer: preliminary results

  • A Obermair, K Czerwenka, C Kurz, P Buxbaum, M Schemper, P Sevela
  • Onkologie 17:4449,
  • 1994
1 Excerpt

Similar Papers

Loading similar papers…