Current methodology for oxygen-15 production for clinical use.

  title={Current methodology for oxygen-15 production for clinical use.},
  author={Jennifer Cook Clark and Christian Crouzel and Geerd J{\"u}rgen Meyer and Karel Strijckmans},
  journal={International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes},
  volume={38 8},
The radionuclide oxygen-15, half-life 2.05 min, is used in simple chemical forms to study oxygen metabolism, blood flow and blood volume in man, using the technique of positron emission tomography (PET). The production of 15O and the preparation of [15O]O2, [15O]CO2, [15O]CO and [15O]H2O is now well established in several PET centres in Europe, North America and Japan. In order to provide a practical design and operational data base for others intending to make use of these techniques an EEC… CONTINUE READING
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