Current measures of metabolic heterogeneity within cervical cancer do not predict disease outcome

@inproceedings{Brooks2011CurrentMO,
  title={Current measures of metabolic heterogeneity within cervical cancer do not predict disease outcome},
  author={Frank J. Brooks and Perry Grigsby},
  booktitle={Radiation oncology},
  year={2011}
}
BACKGROUND A previous study evaluated the intra-tumoral heterogeneity observed in the uptake of F-18 fluorodeoxyglucose (FDG) in pre-treatment positron emission tomography (PET) scans of cancers of the uterine cervix as an indicator of disease outcome. This was done via a novel statistic which ostensibly measured the spatial variations in intra-tumoral metabolic activity. In this work, we argue that statistic is intrinsically non-spatial, and that the apparent delineation between unsuccessfully… CONTINUE READING