Current insights into the "antiphospholipid" syndrome: clinical, immunological, and molecular aspects.

@article{Kandiah1998CurrentII,
  title={Current insights into the "antiphospholipid" syndrome: clinical, immunological, and molecular aspects.},
  author={David Arumaisingam Kandiah and Avni Sali and Yumin Sheng and E. J. White Victoria and David M Marquis and S M Coutts and S A Krilis},
  journal={Advances in immunology},
  year={1998},
  volume={70},
  pages={507-63}
}
Advances in defining the target antigen(s) for the autoantibodies in the APS highlight the inadequacies of the current classification of these autoantibodies into anticardiolipin and LA antibodies. The discovery that beta 2GPI is the target antigen for the autoantibodies detected in solid-phase immunoassays has opened a number of areas of research linking these autoantibodies to atherogenesis and thrombus formation. Although the role of beta 2GPI in the regulation of blood coagulation in… CONTINUE READING
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