Current-distance relation for rewarding brain stimulation.

  title={Current-distance relation for rewarding brain stimulation.},
  author={George Fouriezos and R A Wise},
  journal={Behavioural brain research},
  volume={14 1},
A novel approach to estimating the current density required to directly activate axons involved in the reinforcing effect of brain stimulation is described. Self-stimulating rats received trains of cathodal pulse pairs via two adjacent, stimulating electrodes which were positioned in the lateral hypothalamus and oriented to lie in a plane transverse to the medial forebrain bundle. The first pulse of each pair was delivered through one electrode and, after varied delays, the second was applied… CONTINUE READING