Current concepts on pulmonary host defense mechanisms in children.

  title={Current concepts on pulmonary host defense mechanisms in children.},
  author={Robert W. Wilmott and G Khurana-Hershey and James M Stark},
  journal={Current opinion in pediatrics},
  volume={12 3},
The respiratory tract is exposed continuously to noxious agents, microbial organisms, particles, and allergens. It has therefore evolved both innate and specific defense mechanisms. The innate host defense mechanisms include components such as collectins, beta-defensins, lactoferrin, and complement, all of which have an important role in modulating the immune response. Immune protection of the lungs by specific antibody is reviewed. The airways are protected by alveolar macrophages, neutrophils… CONTINUE READING