Current concepts of cerebral oxygen transport and energy metabolism after severe traumatic brain injury.

@article{Verweij2007CurrentCO,
  title={Current concepts of cerebral oxygen transport and energy metabolism after severe traumatic brain injury.},
  author={B H Verweij and G. Johannes Amelink and Jan Paul Muizelaar},
  journal={Progress in brain research},
  year={2007},
  volume={161},
  pages={111-24}
}
Before energy metabolism can take place, brain cells must be supplied with oxygen and glucose. Only then, in combination with normal mitochondrial function, sufficient energy (adenosine tri-phosphate (ATP)) can be produced. Glucose is virtually the sole fuel for the human brain. The brain lacks fuel stores and requires a continuous supply of glucose and oxygen. Therefore, continuous cerebral blood flow (CBF), cerebral oxygen tension and delivery, and normal mitochondrial function are of vital… CONTINUE READING
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