Current computational methods for prioritizing candidate regulatory polymorphisms.


Discovery of DNA sequence variants responsible for human phenotypic variation is key to advances in molecular diagnostics and medicines. Historically, variants that alter the protein-coding sequence of genes have been targeted when attempting to identify a trait's etiology; this is done because the rules governing these regions are generally well-understood… (More)
DOI: 10.1007/978-1-59745-524-4_5