Current approaches for avoiding the limitations of circulating tumor cells detection methods-implications for diagnosis and treatment of patients with solid tumors.

@article{Kowalik2017CurrentAF,
  title={Current approaches for avoiding the limitations of circulating tumor cells detection methods-implications for diagnosis and treatment of patients with solid tumors.},
  author={Artur Kowalik and Magdalena Kowalewska and Stanisław G{\'o}źdż},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2017},
  volume={185},
  pages={58-84.e15}
}
Eight million people die of cancer each year and 90% of deaths are caused by systemic disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus are the subject of extensive research and an abiding interest to biotechnology and pharmaceutical companies. Recent technological advances have resulted in greatly improved CTC detection, enumeration, expansion, and culture methods. However, despite the fact that nearly 150 years have passed since the first detection and… CONTINUE READING

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