Current and novel therapeutics in the treatment of systemic lupus erythematosus.

@article{YildirimToruner2011CurrentAN,
  title={Current and novel therapeutics in the treatment of systemic lupus erythematosus.},
  author={Cagri Yildirim-Toruner and Betty Diamond},
  journal={The Journal of allergy and clinical immunology},
  year={2011},
  volume={127 2},
  pages={303-12; quiz 313-4}
}
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with significant clinical heterogeneity. Recent advances in our understanding of the genetic, molecular, and cellular bases of autoimmune diseases and especially SLE have led to the application of novel and targeted treatments. Although many treatment modalities are effective in lupus-prone mice, the situation is more complex in human subjects. This article reviews the general approach to the therapy of SLE, focusing on current… CONTINUE READING

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BILAGmeasured improvement in moderately and severely affected body systems in patients with systemic lupus erythematosus (SLE) by epratuzumab: results from Emblem, a phase IIb studyEULAR Meeting

  • K Kalunian, M Petri, F Houssiau, M Pike, B Kilgallen, A Barry
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