Current and future treatment of amyloid diseases.

  title={Current and future treatment of amyloid diseases.},
  author={Maria Ankarcrona and Bengt Winblad and Cecilia Monteiro and Colleen Fearns and Evan T Powers and Jan J Johansson and Gunilla Torstensdotter Westermark and Jenny Presto and B G Ericzon and Jeffery W Kelly},
  journal={Journal of internal medicine},
  volume={280 2},
There are more than 30 human proteins whose aggregation appears to cause degenerative maladies referred to as amyloid diseases or amyloidoses. These disorders are named after the characteristic cross-β-sheet amyloid fibrils that accumulate systemically or are localized to specific organs. In most cases, current treatment is limited to symptomatic approaches and thus disease-modifying therapies are needed. Alzheimer's disease is a neurodegenerative disorder with extracellular amyloid β-peptide… CONTINUE READING
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