Current and future antiviral drug therapies of hepatitis B chronic infection.

@article{Koumbi2015CurrentAF,
  title={Current and future antiviral drug therapies of hepatitis B chronic infection.},
  author={Lemonica Koumbi},
  journal={World journal of hepatology},
  year={2015},
  volume={7 8},
  pages={1030-40}
}
Despite significant improvement in the management of chronic hepatitis B virus (HBV) it remains a public health problem, affecting more than 350 million people worldwide. The natural course of the infection is dynamic and involves a complex interplay between the virus and the host's immune system. Currently the approved therapeutic regimens include pegylated-interferon (IFN)-α and monotherapy with five nucleos(t)ide analogues (NAs). Both antiviral treatments are not capable to eliminate the… CONTINUE READING
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