Current and emerging therapies in multiple sclerosis: a systematic review.

@article{CastroBorrero2012CurrentAE,
  title={Current and emerging therapies in multiple sclerosis: a systematic review.},
  author={Wanda Castro-Borrero and Donna F Graves and Teresa C. Frohman and Angela R. B. Flores and Paula Hardeman and Diana Logan and Megan Orchard and Benjamin D. Greenberg and Elliot M. Frohman},
  journal={Therapeutic advances in neurological disorders},
  year={2012},
  volume={5 4},
  pages={205-20}
}
Multiple sclerosis (MS) is a potentially disabling chronic autoimmune neurological disease that mainly affects young adults. Our understanding of the pathophysiology of MS has significantly advanced in the past quarter of a century. This has led to the development of many disease-modifying therapies (DMTs) that prevent exacerbations and new lesions in patients with relapsing remitting MS (RRMS). So far there is no drug available that can completely halt the neurodegenerative changes associated… CONTINUE READING