Current and emerging molecular targets in glioma.

  title={Current and emerging molecular targets in glioma.},
  author={Rafael Roesler and Andr{\'e} Tesainer Brunetto and Ana Lucia Abujamra and Caroline Brunetto de Farias and Algemir Lunardi Brunetto and Gilberto Schwartsmann},
  journal={Expert review of anticancer therapy},
  volume={10 11},
Gliomas are the most common and lethal neurological cancers. Despite research efforts, the prognosis for patients with malignant gliomas remains poor. Advances in the understanding of cellular and molecular alterations in gliomas have led to the emergence of experimental molecularly targeted therapies. This article summarizes recent progress in the development of targeted therapies for glioma, focusing on emerging molecular targets, including neuropeptide and neurotrophin pathways, glutamate… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 179 references

HER 2 as a cancer stem - cell target

  • Groves, VK Puduvalli, MR Gilbert
  • Lancet Oncol .
  • 2010

Similar Papers

Loading similar papers…