Current and emerging biologics for the treatment of neuromyelitis optica spectrum disorders

@article{Duchow2020CurrentAE,
  title={Current and emerging biologics for the treatment of neuromyelitis optica spectrum disorders},
  author={Ankelien Duchow and Friedemann Paul and Judith Bellmann-Strobl},
  journal={Expert Opinion on Biological Therapy},
  year={2020},
  volume={20},
  pages={1061 - 1072}
}
ABSTRACT Introduction Treatment options for patients suffering from neuromyelitis optica spectrum disorders (NMOSD) so far have relied on off-label and empiric drugs. The first drug for the therapy of anti-aquaporin-4 (AQP4) antibody-seropositive NMOSD patients has been approved in 2019: the C5 complement inhibitor eculizumab. The interleukin-6 receptor inhibitor satralizumab and anti-CD19 antibody inebilizumab have published positive phase III trial results and await approval in the near… Expand
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TLDR
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