Current advances in cell therapy strategies for muscular dystrophies.

  title={Current advances in cell therapy strategies for muscular dystrophies.},
  author={Elisa Negroni and Denis Vallese and J T Vilquin and Gillian Butler-Browne and Vincent Mouly and Capucine Trollet},
  journal={Expert opinion on biological therapy},
  volume={11 2},
INTRODUCTION Muscular dystrophies are a heterogeneous group of genetic diseases characterized by muscle weakness, wasting and degeneration. Cell therapy consists of delivering myogenic precursor cells to damaged tissue for the complementation of missing proteins and/or the regeneration of new muscle fibres. AREAS COVERED We focus on human candidate cells described so far (myoblasts, mesoangioblasts, pericytes, myoendothelial cells, CD133(+) cells, aldehyde-dehydrogenase-positive cells… CONTINUE READING