Current achievements in the production of complex biopharmaceuticals with moss bioreactors

@article{Decker2008CurrentAI,
  title={Current achievements in the production of complex biopharmaceuticals with moss bioreactors},
  author={Eva L. Decker and Ralf Reski},
  journal={Bioprocess and Biosystems Engineering},
  year={2008},
  volume={31},
  pages={3-9}
}
  • E. Decker, R. Reski
  • Published 2008
  • Biology, Engineering
  • Bioprocess and Biosystems Engineering
Transgenic plants are promising alternatives for the low-cost and safe pathogen-free production of complex recombinant pharmaceutical proteins (molecular farming). Plants as higher eukaryotes perform posttranslational modifications similar to those of mammalian cells. However, plant-specific protein N-glycosylation was shown to be immunogenic, a fact that represents a drawback for many plant systems in biopharmaceutical production. The moss Physcomitrella patens offers unique properties as a… 

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