Current Therapeutics, Their Problems, and Sulfur-Containing-Amino-Acid Metabolism as a Novel Target against Infections by “Amitochondriate” Protozoan Parasites

@article{Ali2007CurrentTT,
  title={Current Therapeutics, Their Problems, and Sulfur-Containing-Amino-Acid Metabolism as a Novel Target against Infections by “Amitochondriate” Protozoan Parasites},
  author={V. Ali and T. Nozaki},
  journal={Clinical Microbiology Reviews},
  year={2007},
  volume={20},
  pages={164 - 187}
}
  • V. Ali, T. Nozaki
  • Published 2007
  • Biology, Medicine
  • Clinical Microbiology Reviews
  • SUMMARY The “amitochondriate” protozoan parasites of humans Entamoeba histolytica, Giardia intestinalis, and Trichomonas vaginalis share many biochemical features, e.g., energy and amino acid metabolism, a spectrum of drugs for their treatment, and the occurrence of drug resistance. These parasites possess metabolic pathways that are divergent from those of their mammalian hosts and are often considered to be good targets for drug development. Sulfur-containing-amino-acid metabolism represents… CONTINUE READING
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