Current Therapeutic Strategies and Novel Approaches in Osteosarcoma

  title={Current Therapeutic Strategies and Novel Approaches in Osteosarcoma},
  author={Kosei Ando and M Heymann and Verena Stresing and Kanji Mori and Françoise R{\'e}dini and Dominique Heymann},
Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of cancer-related death in children and adolescents. Although long-term survival in localized osteosarcoma has improved to about 60% during the 1960s and 1970s, long-term survival in both localized and metastatic osteosarcoma has stagnated in the past several decades. Thus, current conventional therapy consists of multi-agent chemotherapy, surgery and radiation, which is not fully adequate for osteosarcoma treatment… CONTINUE READING