Current Status of Dengue Therapeutics Research and Development

  title={Current Status of Dengue Therapeutics Research and Development},
  author={Jenny Guek-Hong Low and Eng Eong Ooi and Subhash G. Vasudevan},
  journal={The Journal of Infectious Diseases},
  pages={S96 - S102}
Abstract Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the… 

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