Current State of ERG as Biomarker in Prostatic Adenocarcinoma.

  title={Current State of ERG as Biomarker in Prostatic Adenocarcinoma.},
  author={Bal{\'a}zs {\'A}cs and Tibor Szarvas and Nora Szekely and P{\'e}ter Nyir{\'a}dy and Attila Marcell Sz{\'a}sz},
  journal={Current cancer drug targets},
  volume={15 8},
In this review we briefly discuss the possible biomarkers of prostate cancer among them we focus and analyze the relevance of TMPRSS2-ERG fusion gene in line with ERG expression in the diagnosis of prostate cancer. Starting at diagnosis and genetic alterations in prostate carcinomas, we examine the incidence and detection of the most common genetic aberration in this tumor and its protein product as well. We also examined the correlation of clinicopathological factors and prognosis with ERG and… CONTINUE READING