Corpus ID: 89321502

Current Review on Genetic Glitch

  title={Current Review on Genetic Glitch},
  author={Bhavani Madhunala},
Genetic Glitches are those which once occur cannot be restored. Glitches can be actually seen in computer programs, Video Games etc. But, here the term ‘Genetic Glitch ‘is used to sort out the things which underwent wrong path at the time of formation of the first Embryo and then its divisions. This is a bit difficult to understand in general words. I will take you in depths of this in order to understand this term Gene Glitch. Because every change that occurs in any part of body of an animal… Expand


Computational Analysis of Mutations in Colon Cancer Genes Reveals a PossibleRole of Micro Satellite in Mutagenesis
This analysis has used the analogy of genome analysis and VIRUS (vital information recourse under siege) and analyzed MLH1, MSH2 and MSH6 gene which play an important role in repairing mistakes made in DNA replication in colon cancer, indicating a positive role of microsatellites in mutagenesis. Expand
Convergence in pigmentation at multiple levels: mutations, genes and function
This work shows that different genes can be responsible for convergent phenotypes even among closely related populations, for example, in the pale beach mice inhabiting Florida's Gulf and Atlantic coasts and shows how convergence can occur at different genetic levels. Expand
Proposal for an allele nomenclature system based on the evolutionary divergence of haplotypes
Knowing knowledge of haplotype patterns, rather than single variant sites, of perhaps several hundred genes will likely be helpful in finding associations between genotype and any multiplex phenotype, and makes haplotype nomenclature more informative than biallelic SNPs. Expand
The probability of genetic parallelism and convergence in natural populations
This work estimated the probability of gene reuse in parallel and convergent phenotypic evolution in nature using data from published studies to suggest that strong biases and constraints affect adaptive evolution, resulting in changes at a relatively small subset of available genes. Expand
Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice.
The results are the first to demonstrate that aminoglycosides can suppress stop codons not only in vitro but also in vivo and raise the possibility of a novel treatment regimen for muscular dystrophy and other diseases caused by premature stop codon mutations. Expand
Molecular and functional basis of phenotypic convergence in white lizards at White Sands
The results demonstrate that even when the same gene is responsible for phenotypic convergence, differences in molecular mechanism can have dramatic consequences on trait expression and ultimately the adaptive trajectory. Expand
Vertebrate pigmentation: from underlying genes to adaptive function.
New and integrative studies of pigmentation genes and their functions have extended into wild populations, providing additional evidence that pigment gene function is largely conserved across disparate vertebrate taxa and can influence adaptive coloration, often in predictable ways. Expand
Misreading of RNA codewords induced by aminoglycoside antibiotics.
The effects observed suggest that aminoglycosides can cause misreadings of only one base at a time in UUU and CCC triplets, but of all three in AAA or III; cause misreading of a base in only the 59 and the internal position in the pyrimidine codons, but in all three positions in the purine codons. Expand
The Evolution of Mutagenesis
A short description and differences among three methods widely used of mutagenesis are shown, with the aim to clarify the relationships often the researchers used the mutagenic approach. Expand
Epilepsy in Multigene Tubulin Family Mutations
The present study summarizes all the published data on tubulin family gene mutations and the associated clinical phenotype in order to define epilepsy recurrence and its characteristics. Expand