Current Progress in Anticalcif ication for Bioprosthetic and Polymeric Heart Valves.
@article{Vyavahare1997CurrentPI, title={Current Progress in Anticalcif ication for Bioprosthetic and Polymeric Heart Valves.}, author={N. Vyavahare and W. Chen and R. R. Joshi and C. Lee and D. Hirsch and J. Levy and F. Schoen and R. Levy}, journal={Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology}, year={1997}, volume={6 4}, pages={ 219-29 } }
The use of bioprosthetic valves fabricated from fixed heterograft tissue (porcine aortic valves or bovine pericardium) in heart valve replacement surgery is limited because of calcification-related failures. The mechanism of calcification of bioprosthetic valves is quite complex and has a variety of determinants, including host factors, tissue fixation conditions, and mechanical effects. Currently, there is no effective therapy to prevent calcification in clinical settings. This article reviews… CONTINUE READING
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