Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

@article{Lerch2017CurrentPO,
  title={Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis},
  author={M. Lerch and C. Mainetti and Benedetta Terziroli Beretta-Piccoli and T. Harr},
  journal={Clinical Reviews in Allergy & Immunology},
  year={2017},
  volume={54},
  pages={147-176}
}
  • M. Lerch, C. Mainetti, +1 author T. Harr
  • Published 2017
  • Medicine
  • Clinical Reviews in Allergy & Immunology
  • Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies and an early recognition and appropriate management is decisive for the survival. SJS/TEN manifest with an “influenza-like” prodromal phase (malaise, fever), followed by painful cutaneous and mucous membrane (ocular, oral, and genital) lesions, and other systemic symptoms. The difference between SJS, SJS/TEN overlap, and… CONTINUE READING
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