Current Concepts of Cerebrovascular Disease — Stroke Oral Contraceptives and Stroke

@inproceedings{Longstreth2005CurrentCO,
  title={Current Concepts of Cerebrovascular Disease — Stroke Oral Contraceptives and Stroke},
  author={William T. Longstreth and Phillip D. Swanson},
  year={2005}
}
IN 1962 LORENTZ described a 41-year-old woman who had an ischemic stroke while taking oral contraceptives. By 1970, 93 cases of ischemic strokes in young women using oral contraceptives had been reported. Establishing that a common exposure, oral contraceptives, causes a rare outcome, stroke, is methodologically challenging. Experimental studies with random allocation of subjects are not possible. Instead, epidemiological, observational studies are needed to distinguish coincidence from… CONTINUE READING