Current Challenges and Trends in the Discovery of Agrochemicals

@article{Lamberth2013CurrentCA,
  title={Current Challenges and Trends in the Discovery of Agrochemicals},
  author={Clemens Lamberth and Stephane Jeanmart and Torsten Luksch and Andrew Plant},
  journal={Science},
  year={2013},
  volume={341},
  pages={742 - 746}
}
Crop protection chemistry has come a long way from its “alchemic” beginnings in the late 19th century to a high-tech science that supports the sustainable production of food, feed, and fiber for a rapidly growing population. Cutting-edge developments in the design and synthesis of agrochemicals help to tackle today’s challenges of weed and pest resistance, higher regulatory safety margins, and higher cost of goods with the invention of selective, environmentally benign, low use rate, and cost… 

Future direction of agrochemical development for plant disease in China

The growth of the global population poses a huge challenge to food security. The continuous application of crop protection products has many negative effects including increased pesticide resistance,

Progress of modern agricultural chemistry and future prospects.

  • P. Jeschke
  • Business, Medicine
    Pest management science
  • 2016
This review gives a comprehensive overview of the innovative products launched over the past 10 years and describes the progress of modern agricultural chemistry and its future prospects.

Synthesis of New Agrochemicals

Given the need for further advances in crop protection, recently developed agrochemicals that can pave the way for future research, such as nanofertilizers, nanopesticides, and nanobiosensors will be described.

Propesticides and their use as agrochemicals.

This review describes comprehensively the successful utilisation of propesticides and their role in syntheses of modern agrochemicals, exemplified by selected commercial products coming from different agrochemical areas.

Chemistry in Agriculture – A Review

Food is the basic requirement for sustenance of human life. Agriculture, for decades, has been closely associated with the cultivation of the soil, production of economically important crops and

EAST MEETS WEST - REGIONAL IMPACT ON AGROCHEMICAL DISCOVERY AND INNOVATION.

It is expected that there will continue to be changes in the numbers and origins of new crop protection compounds, with contributions continuing from Europe, Japan and the US, and increasingly from China.

Biosynthesized Secondary Metabolites for Plant Growth Promotion

The benefits and difficulties associated with pseudomonad-based bioinoculants and recent advances toward commercial application of biosynthetic secondary metabolites from these organisms are described.

Harnessing microbial volatiles to replace pesticides and fertilizers

This review will highlight recent advances in the understanding of the biological activities of microbial VOCs (mVOCs), providing perspectives on research required to develop them into viable alternatives to current unsustainable seasonal inputs.

Latest generation of halogen-containing pesticides.

This review gives an overview of the latest generation of halogen-containing pesticides launched over the past 6 years and describes current halogens-containing development candidates.
...

References

SHOWING 1-10 OF 63 REFERENCES

Chemical crop protection research. Methods and challenges

Abstract Chemical crop protection, today a well-established technology to support sustainable production of food, feed, and fiber, will continue to play an important role in agribusiness in spite of

Chirality and Crop Protection

The modern agrochemical industry is searching, more intensively than ever, for new substances to combat pests (weeds, deleterious insects, plant pathogens, etc.). In the complex and costly selection

Alkyne chemistry in crop protection.

  • C. Lamberth
  • Chemistry
    Bioorganic & medicinal chemistry
  • 2009

Structure-based design of agrochemicals.

  • M. Walter
  • Chemistry
    Natural product reports
  • 2002
This review covers recent advances in the structure-based design of agrochemicals, i.e. herbicides, insecticides, and fungicides, as well as reviewing the literature to the present date.

Physical and Molecular Properties of Agrochemicals: An Analysis of Screen Inputs, Hits, Leads, and Products

Most herbicides and fungicides readily meet the Lipinski 'rule of five' criteria for drug-like compounds with many meeting the more constrained limits reported for pharmaceutical leads.

Innovation in Crop Protection: Trends in Research.

This review spans the development of the crop-protection industry from its earliest beginnings to the present day and attempts to portray how the research-based crop- protection industry is prepared for current and future challenges.

Process Research on the Synthesis of Silthiofam: A Novel Fungicide for Wheat

The development of an efficient, low-cost synthesis of the novel wheat fungicide silthiofam (1) is described. Improvements to the original Discovery route allowed 300 kg of material to be prepared in

Bioactive Heterocyclic Compound Classes: Agrochemicals

DESCRIPTION The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are
...