Current Antipsychotics

  title={Current Antipsychotics},
  author={G. Gross and M. Geyer},
  booktitle={Handbook of Experimental Pharmacology},
Schizophrenia has long been associated with an imbalance in dopamine (DA) neurotransmission, and brain imaging has played an important role in advancing our knowledge and providing evidence for the dopaminergic abnormalities. This chapter reviews the evidence for DA dysfunction in different brain regions in schizophrenia, in particular striatal, extrastriatal, and prefrontal regions, with emphasis on recently published findings. As opposed to the traditional view that most striatal dopaminergic… Expand
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