Curing metastatic cancer: lessons from testicular germ-cell tumours

  title={Curing metastatic cancer: lessons from testicular germ-cell tumours},
  author={J. Masters and B. K{\"o}berle},
  journal={Nature Reviews Cancer},
  • J. Masters, B. Köberle
  • Published 2003
  • Biology, Medicine
  • Nature Reviews Cancer
  • Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers. 
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