Curcuminoids as potent inhibitors of lipid peroxidation.

  title={Curcuminoids as potent inhibitors of lipid peroxidation.},
  author={Sreejayan and Mohan Narasimha Rao},
  journal={The Journal of pharmacy and pharmacology},
  volume={46 12},
Earlier studies showed that curcumin is a potent inhibitor iron-catalysed lipid peroxidation. Demethoxycurcumin, bisdemethoxycurcumin and acetylcurcumin were tested for their ability to inhibit iron-stimulated lipid peroxidation in rat brain homogenate and rat liver microsomes. Comparison of the results with curcumin showed that all compounds are equally active, and more potent than alpha-tocopherol. These results showed that the methoxy and phenolic groups contribute little to the activity… CONTINUE READING


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