Curcumin treatment provides protection against Trypanosoma cruzi infection

@article{Nagajyothi2011CurcuminTP,
  title={Curcumin treatment provides protection against Trypanosoma cruzi infection},
  author={Fnu Nagajyothi and Dazhi Zhao and Louis M Weiss and Herbert B Tanowitz},
  journal={Parasitology Research},
  year={2011},
  volume={110},
  pages={2491-2499}
}
Trypanosoma cruzi, the etiologic agent of Chagas disease, causes an acute myocarditis and chronic cardiomyopathy. The current therapeutic agents for this disease are not always effective and often have severe side effects. Curcumin, a plant polyphenol, has demonstrated a wide range of potential therapeutic effects. In this study, we examined the effect of curcumin on T. cruzi infection in vitro and in vivo. Curcumin pretreatment of fibroblasts inhibited parasite invasion. Treatment reduced the… CONTINUE READING

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References

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Curcumin is an in vivo inhibitor of angiogenesis.

Molecular medicine • 1998
View 4 Excerpts
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