Curcumin treatment provides protection against Trypanosoma cruzi infection

  title={Curcumin treatment provides protection against Trypanosoma cruzi infection},
  author={Fnu Nagajyothi and Dazhi Zhao and Louis M Weiss and Herbert B Tanowitz},
  journal={Parasitology Research},
Trypanosoma cruzi, the etiologic agent of Chagas disease, causes an acute myocarditis and chronic cardiomyopathy. The current therapeutic agents for this disease are not always effective and often have severe side effects. Curcumin, a plant polyphenol, has demonstrated a wide range of potential therapeutic effects. In this study, we examined the effect of curcumin on T. cruzi infection in vitro and in vivo. Curcumin pretreatment of fibroblasts inhibited parasite invasion. Treatment reduced the… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 22 extracted citations

In vitro anthelmintic assessment of selected phytochemicals against Hymenolepis diminuta, a zoonotic tapeworm.

Journal of parasitic diseases : official organ of the Indian Society for Parasitology • 2016
View 3 Excerpts


Publications referenced by this paper.
Showing 1-10 of 34 references

Curcumin is an in vivo inhibitor of angiogenesis.

Molecular medicine • 1998
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…