Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila

@article{Shen2012CurcuminsupplementedDI,
  title={Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila},
  author={Li-rong Shen and Fa Xin Xiao and Peng Yuan and Ying Chen and Qi-kang Gao and Laurence D. Parnell and Mohsen Meydani and Jos{\'e} M. Ordov{\'a}s and Duo Li and Chao-Qiang Lai},
  journal={AGE},
  year={2012},
  volume={35},
  pages={1133-1142}
}
Curcumin is a polyphenolic bioactive compound in turmeric. We examined if antioxidant effects of curcumin are associated with lifespan extension in Drosophila. In this experiment, females and males of Drosophila were fed diets either containing no curcumin (C0) or supplemented with curcumin at 0.5 (C1) and 1.0 (C2) mg/g of diet. The levels of malondialdehyde (MDA), enzyme activity of superoxide dismutase (SOD), and expression of seven age-related genes in females and males were analyzed. We… CONTINUE READING

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