Curcumin protects against ischemia/reperfusion injury in rat kidneys

  title={Curcumin protects against ischemia/reperfusion injury in rat kidneys},
  author={Omer Bayrak and Ebru Uz and Reyhan Bayrak and Faruk Hilmi Turgut and Abdullah Erdem Canda and S Atasaral Sahin and Mehmet Erol Yıldırım and Arif Kaya and Ersin Çimentepe and Ali Akçay},
  journal={World Journal of Urology},
Renal ischemia followed by reperfusion leads to acute renal failure in both native kidneys and renal allograft. We investigated the effect of curcumin on ischemia-reperfusion (I/R) injury and the antioxidant effects of curcumin in rats. Thirty rats were randomly divided into five experimental groups (control, sham, curcumin, I/R and I/R + curcumin, n = 6 each). Curcumin was administered (200 mg kg−1) orally to curcumin and I/R + curcumin groups for 7 days. Then, the rats were subjected to… CONTINUE READING
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