Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB–regulated gene products in IFN-α–sensitive and IFN-α–resistant human bladder cancer cells

@article{Kamat2007CurcuminPT,
  title={Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-$\kappa$B and nuclear factor-$\kappa$B–regulated gene products in IFN-$\alpha$–sensitive and IFN-$\alpha$–resistant human bladder cancer cells},
  author={Ashish M. Kamat and Gautam Sethi and Bharat Bhushan Aggarwal},
  journal={Molecular Cancer Therapeutics},
  year={2007},
  volume={6},
  pages={1022 - 1030}
}
Bladder cancer mortality varies between the countries; whereas being highest in Western countries, it is lowest in Eastern countries, such as India. Cigarette smoking is one of the major risk factors for bladder cancer in affluent nations, such as United States. Localized early-stage bladder cancer is treated with resection and intravesical cytokine therapy, whereas metastatic cancer is typically treated with various combinations of systemic chemotherapy. Whether curcumin, a yellow curry… 
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