Curcumin loaded chitin nanogels for skin cancer treatment via the transdermal route.

@article{Mangalathillam2012CurcuminLC,
  title={Curcumin loaded chitin nanogels for skin cancer treatment via the transdermal route.},
  author={Sabitha Mangalathillam and N. Sanoj Rejinold and Amrita C. Nair and Vinoth-Kumar Lakshmanan and Shantikumar Vasudevan Nair and R Jayakumar},
  journal={Nanoscale},
  year={2012},
  volume={4 1},
  pages={239-50}
}
In this study, curcumin loaded chitin nanogels (CCNGs) were developed using biocompatible and biodegradable chitin with an anticancer curcumin drug. Chitin, as well as curcumin, is insoluble in water. However, the developed CCNGs form a very good and stable dispersion in water. The CCNGs were analyzed by DLS, SEM and FTIR and showed spherical particles in a size range of 70-80 nm. The CCNGs showed higher release at acidic pH compared to neutral pH. The cytotoxicity of the nanogels were analyzed… CONTINUE READING
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