Curcumin is a biologically active copper chelator with antitumor activity.

@article{Zhang2016CurcuminIA,
  title={Curcumin is a biologically active copper chelator with antitumor activity.},
  author={Wei Zhang and Changmai Chen and Hengfei Shi and Manyi Yang and Yu Liu and Ping Ji and Huijun Chen and Ren Xiang Tan and Erguang Li},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2016},
  volume={23 1},
  pages={1-8}
}
BACKGROUND Curcumin is a natural product with antitumor activity. The compound targets multiple cell signaling pathways, including cell survival and proliferation, caspase activation and oncogene expression. As a β-diketone, curcumin also exists as a keto-enol tautomer that chelates transition metal ions with high affinity. PURPOSE Copper has an integral… CONTINUE READING