Curcumin inhibits cardiac hypertrophy and improves cardiovascular function via enhanced Na+/Ca2+ exchanger expression after transverse abdominal aortic constriction in rats.

@article{Bai2018CurcuminIC,
  title={Curcumin inhibits cardiac hypertrophy and improves cardiovascular function via enhanced Na+/Ca2+ exchanger expression after transverse abdominal aortic constriction in rats.},
  author={Xiao-Jie Bai and Jun-Tao Hao and Jin Wang and Wei-fang Zhang and Cai-Ping Yan and Jia-Hui Zhao and Zhi-qing Zhao},
  journal={Pharmacological reports : PR},
  year={2018},
  volume={70 1},
  pages={60-68}
}
BACKGROUND This study tested the hypothesis that inhibition of cardiac hypertrophy and preservation of cardiac/endothelial function by the natural yellow pigment curcumin are associated with upregulated expression of Na+/Ca2+ exchanger (NCX) after transverse aortic constriction (TAC). METHODS Male Wistar rats were subjected to TAC for 10 weeks and… CONTINUE READING