Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT

@inproceedings{Chen2012CurcuminIH,
  title={Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT},
  author={M Y Chen and Ming-Yang Lee and Jing-Jing Chuang and Yi-zhen Li and SIN-TZU Ning and John Chun-Hao Chen and Yi-Wen Liu},
  booktitle={International journal of molecular medicine},
  year={2012}
}
Although hepatitis C virus (HCV) affects approximately 130-170 million people worldwide, no vaccines are available. HCV is an important cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma, leading to the need for liver transplantation. In this study, curcumin, a constituent used in traditional Chinese medicine, has been evaluated for its anti-HCV activity and mechanism, using a human hepatoma cell line containing the HCV genotype 1b subgenomic replicon. Below the concentration of… CONTINUE READING
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