Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways

@inproceedings{Yang2012CurcuminIT,
  title={Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways},
  author={Chu-Wen Yang and Chi-Lun Chang and Hsin-Chen Lee and Chin-Wen Chi and Jia-Ping Pan and Wen-Chin Yang},
  booktitle={BMC complementary and alternative medicine},
  year={2012}
}
BACKGROUND Curcumin is a principal compound of turmeric, commonly used to treat tumors and other diseases. However, its anti-cancer activity in human acute monocytic leukemia THP-1 cells is not clear. This study aimed to study the anti-cancer effect and action of curcumin on THP-1 cells. METHODS THP-1 parental cells and PMA-treated THP-1 cells, were used as in vitro models to evaluate the anti-cancer effect and mechanism of curcumin. Apoptosis and its mechanism were evaluated by WST-1, flow… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 5 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Acute myeloid leukemia.

Hematology/oncology clinics of North America • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…