Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9.

@article{Jiang2013CurcuminIC,
  title={Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9.},
  author={Min Jiang and Ou Huang and Xiaoying Zhang and Zuoquan Xie and Aijun Shen and Hong-chun Liu and Mei-yu Geng and Kun-wei Shen},
  journal={Molecules},
  year={2013},
  volume={18 1},
  pages={701-20}
}
Curcumin, a principal component of turmeric (Curcuma longa), has potential therapeutic activities against breast cancer through multiple signaling pathways. Increasing evidence indicates that curcumin reverses chemo-resistance and sensitizes cancer cells to chemotherapy and targeted therapy in breast cancer. To date, few studies have explored its potential antiproliferation effects and resistance reversal in antiestrogen-resistant breast cancer. In this study, we therefore investigated the… CONTINUE READING
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