Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells

@inproceedings{Wang2017CurcuminEI,
  title={Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells},
  author={Xue Wang and Jiaojiao Deng and Jinxia Yuan and Xin Tang and Yuelong Wang and Hai-Feng Chen and Yi Liu and Liangxue Zhou},
  booktitle={International journal of oncology},
  year={2017}
}
Glioblastoma is the most common brain cancer in adults. It represents one of the top ten malignant tumors with an average survival time of nine months despite treatments with surgery, radiotherapy and chemotherapy. Curcumin is a phytochemical turmeric isolated from root of the Curcuma longa plant. Accumulating evidence have proved that curcumin targets numerous cancer signaling pathways. The E3 ubiquitin ligase NEDD4, neural precursor cell expressed developmentally downregulated protein 4, is… CONTINUE READING