Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involved.

@article{Zhao2012CurcuminEA,
  title={Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involved.},
  author={Xin Ying Zhao and Ying Xu and Qing Zhao and Chang-rui Chen and Ai-Ming Liu and Zhi-Li Huang},
  journal={Neuropharmacology},
  year={2012},
  volume={62 2},
  pages={843-54}
}
Curcumin, a phenolic compound present in Curcuma longa, has been reported to exert antinociceptive effects in some animal models, but the mechanisms remain to be elucidated. This work aimed to investigate the antinociceptive action of curcumin on neuropathic pain and the underlying mechanism(s). Chronic constriction injury (CCI), a canonical animal model of… CONTINUE READING