Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice.

@article{Ueki2013CurcuminAC,
  title={Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice.},
  author={Masaaki Ueki and Masaki Ueno and Jun Sese Shinichi Morishita and Nobuhiro Maekawa},
  journal={Journal of bioscience and bioengineering},
  year={2013},
  volume={115 5},
  pages={547-51}
}
Inflammatory mechanisms may play an important role in the pathogenesis of cisplatin-induced nephrotoxicity. Curcumin is an orange-yellow polyphenol present in curry spice and has anti-inflammatory and antioxidant effects. The purpose of this study was to determine the protective effects of curcumin on cisplatin-induced nephrotoxicity. Mice were randomly divided into four groups: control, cisplatin, cisplatin + curcumin and curcumin. Mice were given cisplatin (20 mg/kg body weight… CONTINUE READING
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