Curcumin Increases the Pathogenicity of Salmonella enterica Serovar Typhimurium in Murine Model

@inproceedings{Marathe2010CurcuminIT,
  title={Curcumin Increases the Pathogenicity of Salmonella enterica Serovar Typhimurium in Murine Model},
  author={Sandhya Amol Marathe and Seemun Ray and Dipshikha Chakravortty},
  booktitle={PloS one},
  year={2010}
}
Curcumin has gained immense importance for its vast therapeutic and prophylactic applications. Contrary to this, our study reveals that it regulates the defense pathways of Salmonella enterica serovar Typhimurium (S. Typhimurium) to enhance its pathogenicity. In a murine model of typhoid fever, we observed higher bacterial load in Peyer's patches, mesenteric lymph node, spleen and liver, when infected with curcumin-treated Salmonella. Curcumin increased the resistance of S. Typhimurium against… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 59 references

Similar Papers

Loading similar papers…