Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells.


BACKGROUND A major challenge in cancer chemotherapy has been developing safe and clinically efficacious chemotherapeutic agents. With its low toxicity profile, curcumin (diferuloylmethane), a naturally occurring flavinoid derived from the rhizome of Curcuma longa, has great promise. In vitro and in vivo preclinical studies have shown its inhibitory… (More)
DOI: 10.1158/1535-7163.MCT-07-2272


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