Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers.

@article{Aggarwal2013CurcuminAO,
  title={Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers.},
  author={Bharat Bhushan Aggarwal and Subash Chandra Gupta and Bokyung Sung},
  journal={British journal of pharmacology},
  year={2013},
  volume={169 8},
  pages={
          1672-92
        }
}
UNLABELLED TNFs are major mediators of inflammation and inflammation-related diseases, hence, the United States Food and Drug Administration (FDA) has approved the use of blockers of the cytokine, TNF-α, for the treatment of osteoarthritis, inflammatory bowel disease, psoriasis and ankylosis. These drugs include the chimeric TNF antibody (infliximab), humanized TNF-α antibody (Humira) and soluble TNF receptor-II (Enbrel) and are associated with a total cumulative market value of more than $20… CONTINUE READING

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