Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia.

@article{Pott2009CuprizoneEO,
  title={Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia.},
  author={Friederike Pott and Stefan Gingele and Tim Clarner and Jon Dang and Werner Baumgartner and Cordian Beyer and Markus Kipp},
  journal={Brain research},
  year={2009},
  volume={1305},
  pages={137-49}
}
Multiple sclerosis is the leading cause of neurological disability in young adults affecting more than two million people worldwide. Although multiple sclerosis is generally considered as white matter disease, distinct pathological alterations are also found in the grey matter. Involvement of basal ganglia seems to be related to a set of symptoms such as fatigue, impaired cognition, and movement disturbance. Since no appropriate animal model for studying cortical deep grey matter demyelination… CONTINUE READING
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