Cumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia.

@article{Saftlas2014CumulativeET,
  title={Cumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia.},
  author={Audrey F. Saftlas and Linda M. Rubenstein and Kaitlin N Prater and Karisa K. Harland and Elizabeth H. Field and Elizabeth W. Triche},
  journal={Journal of reproductive immunology},
  year={2014},
  volume={101-102},
  pages={
          104-110
        }
}
A growing body of literature suggests that prior and prolonged exposure to paternal antigens in seminal fluid induces maternal tolerance to the allogeneic fetus, protecting it from rejection and facilitating successful implantation and placentation. In this case-control study of nulliparous women, we test the hypothesis that increased exposure to paternal seminal fluid via the vaginal or oral route will confer a reduced risk of preeclampsia. Preeclampsia cases (n=258) and normotensive controls… CONTINUE READING

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