Cumulative evaluation of a quantitative immunochemical fecal occult blood test to determine its optimal clinical use.

@article{Rozen2010CumulativeEO,
  title={Cumulative evaluation of a quantitative immunochemical fecal occult blood test to determine its optimal clinical use.},
  author={Paul Rozen and Doron S. Comaneshter and Zohar Levi and Rachel Hazazi and Alex Vilkin and Eran Maoz and Shlomo Birkenfeld and Yaron Niv},
  journal={Cancer},
  year={2010},
  volume={116 9},
  pages={2115-25}
}
BACKGROUND Quantified, human hemoglobin (Hb)-specific, immunochemical fecal occult blood test (IFOBT) measurements are now used for colorectal cancer (CRC) screening. The objective was to evaluate sensitivity and specificity for CRC and advanced adenomatous polyps (APs) by the fecal Hb threshold used to determine a positive test and the number of IFOBTs prepared per test, so as to determine the least number of colonoscopies required to detect a neoplasm. METHODS Cumulative data were analyzed… CONTINUE READING
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