Cumulative effect of 5 daily sessions of θ burst stimulation on corticospinal excitability in amyotrophic lateral sclerosis.

@article{Munneke2013CumulativeEO,
  title={Cumulative effect of 5 daily sessions of θ burst stimulation on corticospinal excitability in amyotrophic lateral sclerosis.},
  author={Moniek A. M. Munneke and Jan J. Rongen and Sebastiaan Overeem and Helenius Jurgen Schelhaas and Machiel J. Zwarts and Dick F. Stegeman},
  journal={Muscle & nerve},
  year={2013},
  volume={48 5},
  pages={733-8}
}
INTRODUCTION Excitotoxicity plays an important role in the pathogenesis of the preferential motor neuron death observed in amyotrophic lateral sclerosis (ALS). Continuous theta burst stimulation (cTBS) by transcranial magnetic stimulation has an inhibitory effect on corticospinal excitability (CSE). We characterized the neurophysiological changes induced by cTBS in ALS. METHODS The patients received 5 daily sessions of cTBS. CSE was assessed at baseline and after each session of cTBS… CONTINUE READING

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