Culture-proven small intestinal bacterial overgrowth as a cause of irritable bowel syndrome: response to lactulose but not broadspectrum antibiotics

@article{Kurtovic2005CultureprovenSI,
  title={Culture-proven small intestinal bacterial overgrowth as a cause of irritable bowel syndrome: response to lactulose but not broadspectrum antibiotics},
  author={Jelica Kurtovic and Isidor Segal and Stephen M. Riordan},
  journal={Journal of Gastroenterology},
  year={2005},
  volume={40},
  pages={767-768}
}
To the Editor: Much recent debate, to which we have contributed, has centered on whether small intestinal bacterial overgrowth (SIBO) may be a cause of the irritable bowel syndrome (IBS).1–6 This possibility had been raised by Pimentel et al.,5 who reported a double-blind, randomized, placebo-controlled study in which normalization of the lactulose breath hydrogen test (LBHT) following antibiotic treatment was found to correlate with symptom improvement in patients with IBS. The same group had… CONTINUE READING

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